Our Leadership: Imagination Over Iteration
Integrating expertise in biochemistry, chemistry, hardware, molecular biology, photonics, semiconductor chips, and software, our leadership has one thing in common: creating solutions no one has thought of yet and disrupting the status quo to make a global impact on medical research that transforms healthcare.
Scientific Advisory Board
Gloria Sheynkman, PhD
Dr. Gloria M. Sheynkman is an Assistant Professor at the University of Virginia, holding a primary appointment in Molecular Physiology and Biological Physics, secondary appointment in Biochemistry and Molecular Genetics, and is a member of the UVA Comprehensive Cancer Center. She earned her B.S. in Biochemistry from the University of Notre Dame and gained early industry experience in the Analytical Development department at Gilead Sciences. She went on to train with Dr. Lloyd Smith—the inventor of automated Sanger sequencing that contributed to the Human Genome Project—where she earned her Ph.D. in Chemistry at the University of Wisconsin–Madison. Following her doctoral work, she trained with Dr. Marc Vidal at the Dana-Farber Cancer Institute and Harvard Medical School, where she advanced high-throughput functional proteomics strategies to characterize protoeforms involved in both normal physiology and disease.
Building on this foundation, Dr. Sheynkman now leads a highly interdisciplinary research group that combines advanced mass spectrometry, long-read RNA sequencing, and single-molecule protein sequencing to map and characterize diverse “proteoforms”—protein isoforms arising from nature’s “variations”, such as alternative splicing and post-translational modifications. Her team employs machine learning and integrative network biology to uncover how these proteoforms drive complex diseases, including cardiovascular disease and cancer.
A recipient of numerous honors—including the American Society for Mass Spectrometry (ASMS) Emerging Investigator distinction and the Tomas A. Hirschfeld Award from the Federation of Analytical Chemistry and Spectroscopy Societies (FACS)—Dr. Sheynkman has published over 40 peer-reviewed papers in her relatively short time as a faculty member. She is active in multiple professional organizations, including the American College of Medical Genetics (ACMG), American Society of Human Genetics (ASHG), Consortium for Top-Down Proteomics (CTDP), Human Proteome Organization (HUPO), and ASMS. She has chaired prominent conference sessions, serves on several NIH study sections, and her research is continuously supported by multiple NIH grants and additional external awards.
In her advisory roles, Dr. Sheynkman brings extensive expertise in bridging genomics with proteomics and a forward-looking perspective on the future of protein measurement technologies.